Abstract: Coal gangue is one of the most significant solid wastes discharged in coal production industry. During open-pit storage, it causes severe environmental risks. Traditional methods for disposing of coal gangue, such as valuable element recovery, mining area filling, construction materials, and soil amendment agents, are often limited by technical bottlenecks such as low reactivity, high risk of heavy metal leaching, high economic costs, and weak disposal capacity, making it difficult to achieve large-scale resource utilization of coal gangue. Based on an analysis of the generation and types of coal gangue, the limitations of existing disposal technologies are systematically reviewed, and the feasibility of coal gangue soilification is demonstrated from aspects including physical and chemical properties, material composition, and natural weathering. Meanwhile, the key obstacles restricting the soil utilization of coal gangue are analyzed from perspectives such as physical structure, salt stress, nutrient imbalance, and heavy metal toxicity. A systematic outlook on the technical path for artificial-driven soilification of coal gangue is presented, proposing a technical framework centered on integrated processes such as mechanical and biological activation to break the inertness of coal gangue minerals, and multi-solid waste collaboration to optimize the substrate structure. The application prospects of artificial-driven coal gangue soilification are demonstrated from the perspectives of environmental ecological safety and economic and policy feasibility. Artificial-driven coal gangue soilification technology is expected to provide a new path for the large-scale disposal of coal gangue and the rational utilization of marginal land.